NMIN Project Database – NMIN – Nanomedicines Innovation Network

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Title	PI	Theme/Program	Host Institution
Neutrophil encapsulation platform for targeted drug delivery	Allen, Christine	Targeted Drug Delivery	University of Toronto
Development of the Metaplex immuno-oncology platform	Bally, Marcel	Targeted Drug Delivery	UBC
Triggered release of anticancer drugs from lipid nanoparticles	Cullis, Pieter	Targeted Drug Delivery	UBC
Nanoparticle formulations for anti-inflammatory IDR peptides	Hancock, Robert	Targeted Drug Delivery	UBC
Nano-delivery of novel inhibitors of DNA repair for enhanced therapy in head & neck cancer	Lavasanifar, Afsaneh	Targeted Drug Delivery	University of Alberta
Targeting myeloid leukemia with nanomedicines	Rossi, Fabio	Targeted Drug Delivery	UBC
Targeting the NLRP3 inflammasome with lipid nanoparticles for the treatment of type 2 diabetes	Verchere, Bruce	Targeted Drug Delivery	UBC
Lipidic nanoparticle formulation of a triple adjuvant for intranasal vaccines	Wasan, Ellen	Targeted Drug Delivery	University of Saskatchewan
Preclinical regulatory plan for CounterFlow-Gauze, a non-compressible hemorrhage control dressing	Kastrup, Christian	Targeted Drug Delivery	UBC
NMIN Theme 1: Research & KTEE Accelerator Project	Li, Shyh-Dar	Targeted Drug Delivery	UBC
Nanoparticle-encapsulated PARPi and ATRi Combination Therapy for the Treatment of Ovarian Cancer	Allen, Christine	Targeted Drug Delivery	University of Toronto
Development of an aerosolized liposomal hydroxychloroquine for treating COVID-19 patients entering hospitals	Bally, Marcel	Targeted Drug Delivery	UBC
Development of a targeted FAST-LNP formulation of cabazitaxel to improve efficacy and safety for prostate cancer treatment	Lewis, John	Targeted Drug Delivery	University of Alberta
Lipid Nanoparticle-mediated Immunotherapy for Pseudomyxoma Peritonei	Li, Shyh-Dar	Targeted Drug Delivery	UBC
Unlocking the full potential of cancer therapy	Chithrani, Devika	Targeted Drug Delivery	University of Victoria
GeneCure: Application of lipid nanoparticle technology to gene therapies in a variety of tissues	Cullis, Pieter	Gene Therapy	UBC
A multiomics screen to identify phagocyte-specific LNPs for immunotherapy	Harder, Kenneth	Gene Therapy	UBC
Development and optimization of LNP-based gene therapy approaches in the brain	Leavitt, Blair	Gene Therapy	UBC
Site-specific laser-mediated gene therapy for corneal endothelial diseases	Meunier, Michel	Gene Therapy	Polytechnique Montreal
Development and utilization of in vivo systems to optimize lipid nanoparticles for therapeutic genome editing: Focus on delivery to muscle for the treatment of LPL Deficiency	Ross, Colin	Gene Therapy	UBC
COVID-19 Therapeutics	Cullis, Pieter	Gene Therapy	UBC
Synthesis and Evaluation of Novel Sulfur-Containing Lipids	Ciufolini, Marco	Gene Therapy	UBC
Developing a Long-Acting Prophylactic Treatment for Hemophilia using siRNA-Mediated Inhibition of Fibrinolysis	Kastrup, Christian	Gene Therapy	UBC
NMIN Theme 2 Research & KTEE Accelerator	Kastrup, Christian	Gene Therapy	UBC
Single-particle measurements to enable rational design of lipid nanoparticle carriers for gene therapies and vaccines	Leslie, Sabrina	Gene Therapy	UBC
Predicting nanoparticle tumour delivery via serum protein adsorption	Chan, Warren	Diagnostics	University of Toronto
Development of an integrated chip for exosome analysis in cancer	Kelley, Shana	Diagnostics	University of Toronto
On-Demand biofunctionalization of lipid nanoparticles for CAR T Cell Therapy	Pardee, Keith	Diagnostics	University of Toronto
A platform to screen for upregulation of soluble calreticulin as a tool to develop nanomedicines targeting acute myeloid leukemia	Walker, Gilbert	Diagnostics	University of Toronto
Customisable metallo-nanotexaphyrins for cancer imaging and therapy	Zheng, Gang	Diagnostics	University of Toronto
NMIN Theme 3: Research & KTEE Accelerator Project	Walker, Gilbert	Diagnostics	University of Toronto
An ultrasensitive digital nanoassay for immunotherapy effectiveness	Wheeler, Aaron	Diagnostics	University of Toronto
Nanoparticle-enhanced, impedance-based biosensor development for cancer diagnostics	Wishart, David	Diagnostics	University of Alberta
PharmaCore: Preclinical Scale-up Manufacturing & Project Management Core Facility	Bally, Marcel	Core Facility	UBC
NanoCore: The Translational NanoMedicines Formulation & Characterization Core Facility	Cullis, Pieter	Core Facility	UBC
eHTA: An early Health Technology Assessment platform	Lynd, Larry	Core Facility	University of British Columbia